Circulating VEGF and TGF-beta1 in children with idiopathic nephrotic syndrome.

  title={Circulating VEGF and TGF-beta1 in children with idiopathic nephrotic syndrome.},
  author={Hae Il Cheong and Jang Han Lee and Hejin P. Hahn and Hye Won Park and Il Soo Ha and Yong Choi},
  journal={Journal of nephrology},
  volume={14 4},
RATIONALE The implications of vascular endothelial growth factor (VEGF) and transforming growth factor-beta (TGF-beta) on the development of proteinuria were studied by measuring the mRNA and protein levels of VEGF and TGF-beta1 in 43 children with primary nephrotic syndrome. METHODS Twenty-seven patients were in the active nephrotic phase at the time of sampling (Group 1), and 16 were in remission (Group 2). In Group 1, 16 were steroid-responders (Group 1a) and 11 were nonresponders (Group… CONTINUE READING
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