Circulating Tumor Cells As Prognostic Markers in Neuroendocrine Tumors

@article{Khan2013CirculatingTC,
  title={Circulating Tumor Cells As Prognostic Markers in Neuroendocrine Tumors},
  author={Mohid S. Khan and Amy A Kirkwood and Theodora Tsigani and Jorge Garc{\'i}a-Hern{\'a}ndez and John A. Hartley and Martyn Evan Caplin and Tim Meyer},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2013},
  volume={31 3},
  pages={
          365-72
        }
}
PURPOSE To determine the prognostic significance of circulating tumor cells (CTCs) in patients with neuroendocrine cancer. PATIENTS AND METHODS In this single-center prospective study, 176 patients with measurable metastatic neuroendocrine tumors (NETs) were recruited. CTCs were measured using a semiautomated technique based on immunomagnetic separation of epithelial cell adhesion molecule-expressing cells. RESULTS Overall, 49% patients had ≥ one CTC, 42% had ≥ two CTCs, and 30% had ≥ five… CONTINUE READING
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