Circulating S100β Protein Is Increased in Intrauterine Growth-Retarded Fetuses

  title={Circulating S100β Protein Is Increased in Intrauterine Growth-Retarded Fetuses},
  author={Diego Gazzolo and Emanuela Marinoni and Romolo di Iorio and Mario Lituania and Pier Luigi Bruschettini and Fabrizio Michetti},
  journal={Pediatric Research},
To determine whether S100β, an acidic calcium-binding protein previously demonstrated as a reliable indicator of a brain lesion, could be helpful in the detection of brain distress in intrauterine growth-retarded (IUGR) fetuses, we studied, by a case-control study, the correlation between S100B protein and the degree of fetoplacental blood flow impairment. Maternal and umbilical blood samples and placental tissue specimens were collected at delivery from IUGR pregnancies with normal (n = 10) or… CONTINUE READING


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Adrenomedullin is increased in the feto-placental circulation in intrauterine growth retardation with abnormal umbilical artery waveforms

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