Circulating MicroRNAs in Plasma of Hepatitis B e Antigen Positive Children Reveal Liver-Specific Target Genes

@inproceedings{Winther2014CirculatingMI,
  title={Circulating MicroRNAs in Plasma of Hepatitis B e Antigen Positive Children Reveal Liver-Specific Target Genes},
  author={Thilde Nordmann Winther and Kari Stougaard Jacobsen and Aashiq Hussain Mirza and Ida Louise Heiberg and Claus Heiner Bang-Berthelsen and Flemming Pociot and Birthe Hogh},
  booktitle={International journal of hepatology},
  year={2014}
}
Background and Aim. Hepatitis B e antigen positive (HBeAg-positive) children are at high risk of severe complications such as hepatocellular carcinoma and cirrhosis. Liver damage is caused by the host immune response to infected hepatocytes, and we hypothesise that specific microRNAs play a role in this complex interaction between virus and host. The study aimed to identify microRNAs with aberrant plasma expressions in HBeAg-positive children and with liver-specific target genes. Methods. By… CONTINUE READING

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Differential plasmamicroRNAprofiles inHBeAg positive andHBeAg negative children with chronic hepatitis B

  • T. N. Winther, C. H. Bang-Berthelsen, I. L. Heiberg, F. Pociot, B.Hogh
  • PLoS ONE, vol. 8, no. 3, Article ID e58236, 2013.
  • 2013
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