Circulating MicroRNAs: Potential Biomarkers for Cancer

  title={Circulating MicroRNAs: Potential Biomarkers for Cancer},
  author={De-Cai Yu and Qing-Guo Li and Xi-Wei Ding and Yi-Tao Ding},
  booktitle={International journal of molecular sciences},
Cancer is the leading cause of death in the world. Development of minimally invasive biomarkers for early detection of cancer is urgently needed to reduce high morbidity and mortality associated with malignancy. MicroRNAs (miRNAs) are small regulatory RNAs that modulate the activity of specific mRNA targets and play important roles in a wide range of physiologic and pathologic processes. Recently, miRNAs were found to be dysregulated in a variety of diseases including cancer. Emerging evidence… CONTINUE READING