Circulating Micro-RNAs as Potential Blood-Based Markers for Early Stage Breast Cancer Detection

@inproceedings{Schrauder2012CirculatingMA,
  title={Circulating Micro-RNAs as Potential Blood-Based Markers for Early Stage Breast Cancer Detection},
  author={Michael G. Schrauder and Reiner Strick and R{\"u}diger Schulz-Wendtland and Pamela L. Strissel and Laura Kahmann and Christian R. Loehberg and Michael P Lux and Sebastian M Jud and Arndt Hartmann and Alexander Hein and Christian Michael Bayer and Mayada R. Bani and Swetlana Richter and Boris R. Adamietz and Evelyn Wenkel and Claudia Rauh and Matthias W. Beckmann and Peter A. Fasching},
  booktitle={PloS one},
  year={2012}
}
INTRODUCTION MicroRNAs (miRNAs, miRs) are a class of small, non-coding RNA molecules with relevance as regulators of gene expression thereby affecting crucial processes in cancer development. MiRNAs offer great potential as biomarkers for cancer detection due to their remarkable stability in blood and their characteristic expression in many different diseases. We investigated whether microarray-based miRNA profiling on whole blood could discriminate between early stage breast cancer patients… CONTINUE READING
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