Circulating Irisin Levels Are Positively Associated with Metabolic Risk Factors in Sedentary Subjects

  title={Circulating Irisin Levels Are Positively Associated with Metabolic Risk Factors in Sedentary Subjects},
  author={Mar{\'i}a Moreno and Jos{\'e} Mar{\'i}a Moreno-Navarrete and Marta Gonz{\'a}lez-Carpio Serrano and Francisco Ortega and El{\'i}as Delgado and Cecilia Sanchez-Ragnarsson and Sergio H. Diaz Valdes and Patricia Botas and Wifredo Ricart and Jos{\'e} Fern{\'a}ndez-Real},
  booktitle={PloS one},
INTRODUCTION A physically active life-style plays an independent role in the protection against type 2 diabetes and cardiovascular diseases. Irisin, a novel exercise-induced myokine, activates thermogenesis in rodents through increasing beige fat cells abundance within white fat. We aimed to investigate circulating irisin levels in association with the degree of physical activity and various metabolic parameters in humans. METHODS Circulating irisin levels (ELISA) and metabolic parameters… CONTINUE READING
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A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

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  • PMID:
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