Circulating Cell-Free DNA and Colorectal Cancer: A Systematic Review

@inproceedings{Vymetalkova2018CirculatingCD,
  title={Circulating Cell-Free DNA and Colorectal Cancer: A Systematic Review},
  author={Veronika Vymetalkova and Klara Cervena and Linda Bartu and Pavel Vodicka},
  booktitle={International journal of molecular sciences},
  year={2018}
}
There is a strong demand for the identification of new biomarkers in colorectal cancer (CRC) diagnosis. Among all liquid biopsy analysts, cell-free circulating DNA (cfDNA) is probably the most promising tool with respect to the identification of minimal residual diseases, assessment of treatment response and prognosis, and identification of resistance mechanisms. Circulating cell-free tumor DNA (ctDNA) maintains the same genomic signatures that are present in the matching tumor tissue allowing… CONTINUE READING

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Special Issue on Basic and Translational Research in Colorectal Cancer

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