Circulating CD8+CD56-perforin+ T cells are increased in multiple sclerosis patients.

@article{Giovanni2011CirculatingCT,
  title={Circulating CD8+CD56-perforin+ T cells are increased in multiple sclerosis patients.},
  author={Frisullo Giovanni and Plantone Domenico and Marti Alessandro and Iorio Raffaele and Nociti Viviana and Patanella Agata Katia and Batocchi Anna Paola},
  journal={Journal of neuroimmunology},
  year={2011},
  volume={240-241},
  pages={137-41}
}
Relapsing-remitting multiple sclerosis (RRMS), secondary progressive (SP)MS and primary progressive (PP)MS patients showed higher percentages of circulating CD8+CD56-perforin+ T cells than controls whereas only relapsing RRMS and PPMS patients showed higher perforin expression in CD8+CD56- T cells than controls. MS patients with EDSS ≥3 showed higher percentage of CD8+CD56-perforin+ T cells than patients with EDSS <3 and controls whereas patients with EDSS <3 showed higher percentage of this T… CONTINUE READING