Corpus ID: 43460101

Circulating Bmi-1 mRNA as a diagnostic and prognostic biomarker for non-small cell lung cancer

  title={Circulating Bmi-1 mRNA as a diagnostic and prognostic biomarker for non-small cell lung cancer},
  author={Q Hou and Chao Zhao and Xiangyan Wang and Hubo Shi},
Bmi-1, a key member of the Polycomb group complex, has been shown in non-small cell lung cancer (NSCLC) tumorigenesis and progress. The aim of this study was to detect the levels of circulating Bmi-1 mRNA in plasma of NSCLC patients and evaluate its diagnostic and prognostic value. Levels of circulating Bmi-1 mRNA were detected by reverse transcription quantitative real-time PCR in plasma of 108 NSCLC patients and 40 healthy controls. The results showed that circulating Bmi-1 mRNA levels were… Expand
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