Circulating α-klotho levels in CKD and relationship to progression.

  title={Circulating α-klotho levels in CKD and relationship to progression.},
  author={Hyoung R. Kim and Bo Young Nam and Dong Wook Kim and Min Woong Kang and Jae-Hyun Han and Mi Jung Lee and Dong Ho Shin and Fa Mee Doh and Hyang Mo Koo and Kwang Il Ko and Chan Kim and Hyung Jung Oh and Tae Hyun Yoo and Shin-Wook Kang and Dae Suk Han and Seung Hyeok Han},
  journal={American journal of kidney diseases : the official journal of the National Kidney Foundation},
  volume={61 6},
BACKGROUND α-Klotho is reported to have protective effects against kidney injury, and its renal expression is decreased in many experimental models of kidney disease. However, circulating α-klotho levels in human chronic kidney disease (CKD) and the relationship to progression are unknown. STUDY DESIGN Post hoc analysis of a prospective cohort study. SETTING & PARTICIPANTS 243 of 301 participants from a CKD cohort at our institution between January 2006 and December 2011 were eligible for… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 34 extracted citations

The effect of nephrectomy on Klotho, FGF-23 and bone metabolism

International Urology and Nephrology • 2017
View 5 Excerpts
Highly Influenced

Is Klotho deficiency independently associated with cardiovascular risk in chronic kidney disease?

Kidney research and clinical practice • 2016
View 5 Excerpts
Highly Influenced


Publications referenced by this paper.
Showing 1-10 of 45 references

Soluble klotho and autosomal dominant polycystic kidney disease.

Clinical journal of the American Society of Nephrology : CJASN • 2012

Similar Papers

Loading similar papers…