Circular permuted proteins in the universe of protein folds

@article{SchmidtGoenner2010CircularPP,
  title={Circular permuted proteins in the universe of protein folds},
  author={Tobias Schmidt-Goenner and Aysam Guerler and Bjoern Kolbeck and Ernst-Walter Knapp},
  journal={Proteins: Structure},
  year={2010},
  volume={78}
}
Finding and identifying circular permuted protein pairs (CPP) is one of the harder tasks for structure alignment programs, because of the different location of the break in the polypeptide chain connectivity. The protein structure alignment tool GANGSTA+ was used to search for CPPs in a database of nearly 10,000 protein structures. It also allows determination of the statistical significance of the occurrence of circular permutations in the protein universe. The number of detected CPPs was… 
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