Circular RNA circCSNK1G3 induces HOXA10 signaling and promotes the growth and metastasis of lung adenocarcinoma cells through hsa-miR-143-3p sponging.

@article{Lu2020CircularRC,
  title={Circular RNA circCSNK1G3 induces HOXA10 signaling and promotes the growth and metastasis of lung adenocarcinoma cells through hsa-miR-143-3p sponging.},
  author={T. Lu and Tong Qiu and B. Han and Yuanyong Wang and Xiao Sun and Y. Qin and Ao Liu and N. Ge and W. Jiao},
  journal={Cellular oncology},
  year={2020}
}
BACKGROUND In the last decade, a relatively novel, ubiquitous and highly stable subclass of non-coding RNAs, called circular (circ)-RNAs, has increasingly been implicated in cancer development, and several of them have been shown to act as microRNA sponges. As yet, however, the role of circRNAs in lung adenocarcinoma (LUAD) development has largely remained unexplored. METHODS Bioinformatics, microarray-based and qRT-PCR expression assays were used to assess circRNA, miRNA and mRNA expression… Expand

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