Circular RNA circCSNK1G3 induces HOXA10 signaling and promotes the growth and metastasis of lung adenocarcinoma cells through hsa-miR-143-3p sponging.
@article{Lu2020CircularRC, title={Circular RNA circCSNK1G3 induces HOXA10 signaling and promotes the growth and metastasis of lung adenocarcinoma cells through hsa-miR-143-3p sponging.}, author={T. Lu and Tong Qiu and B. Han and Yuanyong Wang and Xiao Sun and Y. Qin and Ao Liu and N. Ge and W. Jiao}, journal={Cellular oncology}, year={2020} }
BACKGROUND
In the last decade, a relatively novel, ubiquitous and highly stable subclass of non-coding RNAs, called circular (circ)-RNAs, has increasingly been implicated in cancer development, and several of them have been shown to act as microRNA sponges. As yet, however, the role of circRNAs in lung adenocarcinoma (LUAD) development has largely remained unexplored.
METHODS
Bioinformatics, microarray-based and qRT-PCR expression assays were used to assess circRNA, miRNA and mRNA expression… Expand
References
SHOWING 1-10 OF 43 REFERENCES
Circular RNA circPVT1 Promotes Proliferation and Invasion Through Sponging miR-125b and Activating E2F2 Signaling in Non-Small Cell Lung Cancer
- Medicine, Biology
- Cellular Physiology and Biochemistry
- 2018
- 48
EIF4A3-induced circular RNA MMP9 (circMMP9) acts as a sponge of miR-124 and promotes glioblastoma multiforme cell tumorigenesis
- Biology, Medicine
- Molecular Cancer
- 2018
- 97
Circular RNA_LARP4 inhibits cell proliferation and invasion of gastric cancer by sponging miR-424-5p and regulating LATS1 expression
- Biology, Medicine
- Molecular Cancer
- 2017
- 293
Increased Expression of Circular RNA circ_0005230 Indicates Dismal Prognosis in Breast Cancer and Regulates Cell Proliferation and Invasion via miR-618/ CBX8 Signal Pathway
- Biology, Medicine
- Cellular Physiology and Biochemistry
- 2018
- 40
Circular RNA BCRC-3 suppresses bladder cancer proliferation through miR-182-5p/p27 axis
- Biology, Medicine
- Molecular Cancer
- 2018
- 91
Circular RNA circMTO1 acts as the sponge of microRNA‐9 to suppress hepatocellular carcinoma progression
- Biology, Medicine
- Hepatology
- 2017
- 605
Circ-SFMBT2 promotes the proliferation of gastric cancer cells through sponging miR-182-5p to enhance CREB1 expression
- Biology, Medicine
- Cancer management and research
- 2018
- 46
- PDF
Circular RNA circ-ABCB10 promotes breast cancer proliferation and progression through sponging miR-1271.
- Medicine
- American journal of cancer research
- 2017
- 186
- PDF
Circular BANP, an upregulated circular RNA that modulates cell proliferation in colorectal cancer.
- Biology, Medicine
- Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
- 2017
- 110
The Circular RNA circPRKCI Promotes Tumor Growth in Lung Adenocarcinoma.
- Biology, Medicine
- Cancer research
- 2018
- 124
- PDF