Circular RNA: a new star in neurological diseases.

  title={Circular RNA: a new star in neurological diseases.},
  author={Tao-Ran Li and Yan-Jie Jia and Qun Wang and Xiao-Qiu Shao and Rui-Juan Lv},
  journal={The International journal of neuroscience},
  volume={127 8},
Circular RNAs (circRNAs) are novel endogenous non-coding RNAs characterized by the presence of a covalent bond linking the 3' and 5' ends generated by backsplicing. In this review, we summarize a number of the latest theories regarding the biogenesis, properties and functions of circRNAs. Specifically, we focus on the advancing characteristics and functions of circRNAs in the brain and neurological diseases. CircRNAs exhibit the characteristics of species conservation, abundance and tissue… CONTINUE READING
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