Circuits regulating pleasure and happiness in major depression.

@article{Loonen2016CircuitsRP,
  title={Circuits regulating pleasure and happiness in major depression.},
  author={Anton J M Loonen and Svetlana A. Ivanova},
  journal={Medical hypotheses},
  year={2016},
  volume={87},
  pages={14-21}
}
The introduction of selective serotonin reuptake inhibitors has gradually changed the borders of the major depression disease class. Anhedonia was considered a cardinal symptom of endogenous depression, but the potential of selective serotonin reuptake inhibitors to treat anxiety disorders has increased the relevance of stress-induced morbidity. This shift has led to an important heterogeneity of current major depressive disorder. The complexity can be disentangled by postulating the existence… CONTINUE READING