Circannual rhythm in natural killer activity and mitogen responsiveness of murine splenocytes.

@article{Pati1987CircannualRI,
  title={Circannual rhythm in natural killer activity and mitogen responsiveness of murine splenocytes.},
  author={Atanu Kumar Pati and I. Florentin and Vincent Chung and Martine De Sousa and Francis A L{\'e}vi and Georges Math{\'e}},
  journal={Cellular immunology},
  year={1987},
  volume={108 1},
  pages={227-34}
}
Seasonal variations were observed in murine splenic natural killer (NK) cell activity and also in murine lymphocyte responsiveness to mitogens, namely, concanavalin A, phytohemagglutinin, and lipopolysaccharide. The maximum and minimum splenic NK cell activities were observed in January-February and July-August, respectively. Conversely, maxima and minima of lymphoproliferative responses to all the three mitogens occurred in April-June and January-February, respectively. Such variations, when… CONTINUE READING