Circadian variations in antioxidant defences and lipid peroxidation in the rat heart.

@article{Lapenna1992CircadianVI,
  title={Circadian variations in antioxidant defences and lipid peroxidation in the rat heart.},
  author={Domenico Lapenna and S de Gioia and Andrea Mezzetti and Ettore Porreca and Giuliano Ciofani and Leonardo Marzio and Fabio Capani and Carmine di Ilio and Franco Cuccurullo},
  journal={Free radical research communications},
  year={1992},
  volume={17 3},
  pages={187-94}
}
Circadian variations in antioxidant defences and lipid peroxidation were investigated in 12 rat hearts perfused during light (i.e., at 08.00, n = 6) and dark cycle (i.e., at 19.00, n = 6). Higher levels of non proteic thiol compounds (P < 0.01), glutathione transferase activity (P < 0.05) and lipid peroxidation (P < 0.01) were detected in evening-excised hearts, associated with a lower (P < 0.05) selenium-dependent glutathione peroxidase activity; superoxide dismutase and glutathione reductase… CONTINUE READING

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