Circadian variation and triggering of acute coronary events.

  title={Circadian variation and triggering of acute coronary events.},
  author={J. F. Esteban Muller},
  journal={American heart journal},
  volume={137 4 Pt 2},
The recognition that the onset of cardiovascular events follows a circadian periodicity and is frequently triggered by physical or mental stresses has created new possibilities for disease prevention. Morning peaks in occurrence are now well-documented for acute myocardial infarction, sudden cardiac death, transient myocardial ischemia, and ischemic stroke. The morning increase in events begins after subjects assume an upright posture and start the day's activities, during a time of sympathetic… CONTINUE READING


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