Circadian rhythmicity in dopamine content of mammalian retina: role of the photoreceptors.

@article{Doyle2002CircadianRI,
  title={Circadian rhythmicity in dopamine content of mammalian retina: role of the photoreceptors.},
  author={Susan E. Doyle and Wilson E McIvor and Michael Menaker},
  journal={Journal of neurochemistry},
  year={2002},
  volume={83 1},
  pages={211-9}
}
Dopamine, the predominant retinal catecholamine, is a neurotransmitter and neuromodulator known to regulate light-adaptive retinal processes. Because dopamine influences several rhythmic events in the retina it is also a candidate for a retinal circadian signal. Using high performance liquid chromatography (HPLC), we have tested whether dopamine and its breakdown products are rhythmic in Royal College of Surgeons (RCS) rats with normal and dystrophic retinas. In both normal and mutant animals… CONTINUE READING
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