Circadian rhythm sleep disorders: characteristics and entrainment pathology in delayed sleep phase and non-24-h sleep-wake syndrome.

@article{Okawa2007CircadianRS,
  title={Circadian rhythm sleep disorders: characteristics and entrainment pathology in delayed sleep phase and non-24-h sleep-wake syndrome.},
  author={Masako Okawa and Makoto Uchiyama},
  journal={Sleep medicine reviews},
  year={2007},
  volume={11 6},
  pages={
          485-96
        }
}
  • M. OkawaM. Uchiyama
  • Published 1 December 2007
  • Psychology, Medicine, Biology
  • Sleep medicine reviews

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References

SHOWING 1-10 OF 110 REFERENCES

Poor compensatory function for sleep loss as a pathogenic factor in patients with delayed sleep phase syndrome.

It is suggested that poor compensatory function for sleep loss predisposes DSPS patients to failure to reset their sleep phase and provides implications for understanding not only the pathophysiology of DSPS but also the biological basis for why some people can change their sleep schedule easily according to personal or social demands while others cannot.

The delayed sleep phase syndrome: clinical and investigative findings in 14 subjects.

The syndrome causes severe disruption to education, work and family life, and different patterns of sleep phase delay seen in the syndrome include stable, progressive, irregular and non-24 hour sleep-wake cycles.

Circadian rhythm sleep disorders in adolescents: Clinical trials of combined treatments based on chronobiology

A step‐by‐step procedure of combined treatments for the circadian rhythm sleep disorders is proposed, based on clinical studies of patients with delayed sleep phase syndrome and non‐24‐h sleep–wake rhythm.

Non-24-hour sleep-wake syndrome in a sighted man: circadian rhythm studies and efficacy of melatonin treatment.

The case of a 41-year-old sighted man with non-24-hour sleep-wake syndrome is presented and it is revealed that the patient appeared to be subsensitive to bright light.

Clinical characteristics of circadian rhythm sleep disorders

Difficulty in adapting to social life was more severe in patients with non‐24 than in those with DSPS, and it was of psychiatric interest that a considerable number of patients had depressive states in the course of their circadian rhythm sleep disorders.

Delayed sleep phase syndrome. A chronobiological disorder with sleep-onset insomnia.

A new syndrome called "delayed sleep phase insomnia" is described, which is proposed to be a disorder of the circadian sleep-wake rhythm in which the "advance" portion of the phase response curve is small.

Familial advanced sleep-phase syndrome: A short-period circadian rhythm variant in humans

Three kindreds with a profound phase advance of the sleep–wake, melatonin and temperature rhythms associated with a very short τ represent a well-characterized familial circadian rhythm variant in humans and provide a unique opportunity for genetic analysis of human circadian physiology.

Larger phase angle between sleep propensity and melatonin rhythms in sighted humans with non-24-hour sleep-wake syndrome.

It was postulated that Non-24 sufferers' delayed SP onset relative to the circadian pacemaker may accelerate the light-induced phase-delay, leading to sleep-wake cycle that is longer than 24 hours.

Melatonin Rhythms in Delayed Sleep Phase Syndrome

The alteration of phase angle between melatonin rhythm and sleep phase suggested that not only the delay of the circadian clock but also a functional disturbance of the sleep-wake mechanism underlies delayed sleep phase syndrome.
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