Circadian rhythm of rest activity and autonomic nervous system activity at different stages in Parkinson's disease.

@article{Niwa2011CircadianRO,
  title={Circadian rhythm of rest activity and autonomic nervous system activity at different stages in Parkinson's disease.},
  author={Fumitoshi Niwa and Nagato Kuriyama and Masanori Nakagawa and Jiro Imanishi},
  journal={Autonomic neuroscience : basic & clinical},
  year={2011},
  volume={165 2},
  pages={195-200}
}
Patients with Parkinson's disease (PD) often suffer from non-motor symptoms, including sleep and autonomic dysfunctions, controlled by circadian regulation. To evaluate the alteration of circadian rhythm in PD patients, we investigated both rest activities and autonomic functions. Twenty-seven patients with idiopathic PD and 30 age-matched control subjects were recruited. Group comparisons of controls (mean age: 68.93 years), early-PD patients classified as Hoehn-Yahr (HY) stage 1&2 (mean age… CONTINUE READING

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