Circadian rhythm of plasma sodium is disrupted in spontaneously hypertensive rats fed a high-NaCl diet.

@article{Fang2000CircadianRO,
  title={Circadian rhythm of plasma sodium is disrupted in spontaneously hypertensive rats fed a high-NaCl diet.},
  author={Z Fang and Scott H Carlson and Ning Peng and J. Michael Wyss},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2000},
  volume={278 6},
  pages={R1490-5}
}
High-NaCl diets elevate arterial pressure in NaCl-sensitive individuals, and increases in plasma sodium may trigger this effect. The present study tests the hypotheses that 1) plasma sodium displays a circadian rhythm in rats, 2) the plasma sodium rhythm is disturbed in spontaneously hypertensive rats (SHR), and 3) excess dietary NaCl elevates plasma sodium concentration in SHR. The results demonstrate that plasma sodium has a circadian rhythm that is inversely related to the circadian rhythm… CONTINUE READING
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