Circadian rhythm of double (rate-pressure) product in healthy normotensive young subjects.

@article{Hermida2001CircadianRO,
  title={Circadian rhythm of double (rate-pressure) product in healthy normotensive young subjects.},
  author={Ram{\'o}n C. Hermida and Jos{\'e} Ram{\'o}n Fern{\'a}ndez and Diana Elva Ayala and Artemio Moj{\'o}n and I Casares Alonso and Michael hale Smolensky},
  journal={Chronobiology international},
  year={2001},
  volume={18 3},
  pages={475-89}
}
The double product (DP), systolic blood pressure multiplied by heart rate, is a surrogate measure of myocardial oxygen demand and cardiac workload used increasingly today in medicine. The double product is more strongly correlated with left ventricular mass than the daily blood pressure mean. The purpose of this study was to describe the normative circadian pattern of the double product in healthy normotensive young adults. We studied 125 men and 75 women, 23.0+/-3.3 (mean +/- SD) years of age… CONTINUE READING

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