Circadian rhythm of clock genes in human adipose explants.

  title={Circadian rhythm of clock genes in human adipose explants.},
  author={Cecilia G{\'o}mez-Santos and Purificaci{\'o}n G{\'o}mez-Abell{\'a}n and Juan Antonio Madrid and Juan Jos{\'e} Hern{\'a}ndez-Morante and Juan Antonio Luj{\'a}n and Jos{\'e} M. Ordov{\'a}s and Marta Garaulet},
  volume={17 8},
To analyze in severely obese women the circadian expression of the clock genes hPer2, hBmal1, and hCry1 in explants from subcutaneous (SAT) and visceral (VAT) adipose tissue (AT), in order to elucidate whether this circadian clockwork can oscillate accurately and independently of the suprachiasmatic nucleus (SCN) and if glucocorticoid metabolism-related genes such as glucocorticoid receptor (hGr) and 11beta-hydroxysteroid dehydrogenase 1 (h11 beta Hsd1) and the transcription factor peroxisome… CONTINUE READING
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