Circadian rhythm in rest and activity: a biological correlate of quality of life and a predictor of survival in patients with metastatic colorectal cancer.

@article{Innominato2009CircadianRI,
  title={Circadian rhythm in rest and activity: a biological correlate of quality of life and a predictor of survival in patients with metastatic colorectal cancer.},
  author={Pasquale F Innominato and Christian Focan and Thierry Gorlia and Thierry Moreau and Carlo Garufi and James Waterhouse and Sylvie Giacchetti and Bruno Coudert and Stefano Iacobelli and Dominique Genet and Marco Tampellini and Philippe Chollet and M Sue Lentz and M Christine Mormont and Francis A L{\'e}vi and Georg A. Bjarnason},
  journal={Cancer research},
  year={2009},
  volume={69 11},
  pages={4700-7}
}
The rest-activity circadian rhythm (CircAct) reflects the function of the circadian timing system. In a prior single-institution study, the extent of CircAct perturbation independently predicted for survival and tumor response in 192 patients receiving chemotherapy for metastatic colorectal cancer. Moreover, the main CircAct parameters correlated with several health-related quality of life (HRQoL) scales. In this prospective study, we attempted to extend these results to an independent cohort… CONTINUE READING
49 Extracted Citations
51 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 49 extracted citations

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 51 references

Impaired sleep Research

  • K Lee, M Cho, C Miaskowski, M. Dodd
  • on May
  • 2009

Similar Papers

Loading similar papers…