Circadian rhythm and cardiovascular disease

@article{Shaw2009CircadianRA,
  title={Circadian rhythm and cardiovascular disease},
  author={Elizabeth Shaw and Geoffrey H Tofler},
  journal={Current Atherosclerosis Reports},
  year={2009},
  volume={11},
  pages={289-295}
}
  • E. ShawG. Tofler
  • Published 14 June 2009
  • Medicine, Biology
  • Current Atherosclerosis Reports
The demonstration of a circadian variation in frequency of onset of myocardial infarction, sudden cardiac death, and stroke provides an opportunity to gain insight into the mechanism of transformation from chronic stable to acute unstable manifestation of cardiovascular disease. Contributing physiologic changes that exhibit a morning peak include arterial pressure, heart rate, and vascular tone, which promote plaque rupture, together with increased platelet reactivity and reduced fibrinolytic… 

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