Circadian plasma level profile of lisuride in rats and mice after continuous administration via the diet.

@article{Krause1995CircadianPL,
  title={Circadian plasma level profile of lisuride in rats and mice after continuous administration via the diet.},
  author={Werner Krause and F Reissmann and Guido Kuehne and C Sch{\"o}bel},
  journal={Arzneimittel-Forschung},
  year={1995},
  volume={45 1},
  pages={6-10}
}
Lisuride (Dopergin, CAS 18016-80-3), a dopamine D2 agonist, was administered to male and female rats and mice continuously via the diet for 14 days. The doses were 0.2 mg/kg/d in mice and 1 mg/kg/d in mice and rats. Plasma level profiles (0-22 or 24 h) were determined by measuring lisuride concentrations by radioimmunoassay. At all doses a plateau-like… CONTINUE READING