Circadian photoreception in the retinally degenerate mouse (rd/rd)

  title={Circadian photoreception in the retinally degenerate mouse (rd/rd)},
  author={Russell G. Foster and Ignacio Provencio and David J. Hudson and S M Fiske and W. J. de Grip and Michael Menaker},
  journal={Journal of Comparative Physiology A},
SummaryWe have examined the effects of light on circadian locomotor rhythms in retinally degenerate mice (C57BL/6J mice homozygous for the rd allele: rd/rd). The sensitivity of circadian photoreception in these mice was determined by varying the irradiance of a 15 min light pulse (515 nm) given at circadian time 16 and meauring the magnitude of the phase shift of the locomotor rhythm. Experiments were performed on animals 80 days of age. Despite the loss of visual photoreceptors in the rd/rd… 

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