Circadian oscillation of photopigment transcript levels in the mouse retina.

  title={Circadian oscillation of photopigment transcript levels in the mouse retina.},
  author={Malcolm von Schantz and Robert J Lucas and Russel G. Foster},
  journal={Brain research. Molecular brain research},
  volume={72 1},
The mammalian retina contains an autonomous circadian oscillator that can sustain rhythms in outer segment disc shedding and melatonin synthesis even in the absence of cues from the central oscillator in the suprachiasmatic nucleus (SCN). The present investigation aimed to ascertain whether the steady-state levels of rod and cone opsin mRNA exhibited a circadian oscillation in the mouse, and if so, to characterise this oscillation with regard to phase. Retinas were collected from mice free… CONTINUE READING

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