Circadian clocks and cell division: what's the pacemaker?

@article{Johnson2010CircadianCA,
  title={Circadian clocks and cell division: what's the pacemaker?},
  author={Carl Hirschie Johnson},
  journal={Cell cycle},
  year={2010},
  volume={9 19},
  pages={3864-73}
}
Evolution has selected a system of two intertwined cell cycles: the cell division cycle (CDC) and the daily (circadian) biological clock. The circadian clock keeps track of solar time and programs biological processes to occur at environmentally appropriate times. One of these processes is the CDC, which is often gated by the circadian clock. The intermeshing of these two cell cycles is probably responsible for the observation that disruption of the circadian system enhances susceptibility to… CONTINUE READING

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