Circadian clock regulates response to pesticides in Drosophila via conserved Pdp1 pathway.

@article{Beaver2010CircadianCR,
  title={Circadian clock regulates response to pesticides in Drosophila via conserved Pdp1 pathway.},
  author={Laura M Beaver and Louisa Ada Hooven and Shawn Michael Butcher and Natraj Krishnan and Katherine Alice Sherman and Eileen Shin-Yeu Chow and Jadwiga Maria Giebultowicz},
  journal={Toxicological sciences : an official journal of the Society of Toxicology},
  year={2010},
  volume={115 2},
  pages={513-20}
}
Daily rhythms generated by the circadian clock regulate many life functions, including responses to xenobiotic compounds. In Drosophila melanogaster, the circadian clock consists of positive elements encoded by cycle (cyc) and Clock (Clk) and negative elements encoded by period (per) and timeless (tim) genes. The epsilon-isoform of the PAR-domain protein 1 (Pdp1epsilon) transcription factor is controlled by positive clock elements and regulates daily locomotor activity rhythms. Pdp1 target… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

Similar Papers

Loading similar papers…