Circadian Mechanisms Underlying Reward-Related Neurophysiology and Synaptic Plasticity

  title={Circadian Mechanisms Underlying Reward-Related Neurophysiology and Synaptic Plasticity},
  author={Puja K. Parekh and Colleen A McClung},
  booktitle={Front. Psychiatry},
Evidence from clinical and preclinical research provides an undeniable link between disruptions in the circadian clock and the development of psychiatric diseases, including mood and substance abuse disorders. The molecular clock, which controls daily patterns of physiological and behavioral activity in living organisms, when desynchronized, may exacerbate or precipitate symptoms of psychiatric illness. One of the outstanding questions remaining in this field is that of cause and effect in the… CONTINUE READING
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