Circadian Clues to Sleep Onset Mechanisms

  title={Circadian Clues to Sleep Onset Mechanisms},
  author={Kurt Kr{\"a}uchi and Anna M Wirz-Justice},
Thermoregulatory processes have long been implicated in initiation of human sleep. A meta-analysis of studies carried out under the controlled conditions of a constant routine protocol followed by nocturnal sleep revealed that heat loss, indirectly measured by the distal-proximal skin temperature gradient, was the best predictor variable for sleep onset latency (compared with core body temperature or its rate of change, heart rate, melatonin onset, and subjective sleepiness ratings). The… CONTINUE READING
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Circadian and homeostatic regulation of core body temperature and alertness in humans: what is the role of melatonin

  • K Kräuchi, C Cajochen, A Wirz-Justice
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Wirz-Justice A (1999b): Interaction of melatonin with core body cooling: sleepiness is primarily associated with heat loss and not with a decrease in core body temperature

  • K Kräuchi, E Werth, D Wüest, C Renz
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Thermoregulatory changes occur after lights off not after onset of sleep stage 2

  • K Kräuchi, C Cajochen, E Werth, C Renz, M vonArb, A Wirz-Justice
  • 2001
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