CircRNA ZFR stimulates the proliferation of hepatocellular carcinoma through upregulating MAP2K1.

  title={CircRNA ZFR stimulates the proliferation of hepatocellular carcinoma through upregulating MAP2K1.},
  author={Blanpain C{\'e}dric and Tapara Dramani Maman Souraka and Y-l Feng and P Kisembo and Jiancheng Tu},
  journal={European review for medical and pharmacological sciences},
  volume={24 19},
OBJECTIVE The aim of the study was to illustrate the function of circRNA ZFR in aggravating the development of hepatocellular carcinoma (HCC) by upregulating MAP2K1. PATIENTS AND METHODS CircRNA ZFR levels in 62 paired HCC and paracancerous species were detected. The influence of circRNA ZFR on clinical data of HCC patients was analyzed. After the overexpression or knockdown of circRNA ZFR, changes in viability and clonality of Bel-7402 and Hep3B cells were assessed, respectively. The… 

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