Circ-ZKSCAN1 regulates FAM83A expression and inactivates MAPK signaling by targeting miR-330-5p to promote non-small cell lung cancer progression.

@article{Wang2019CircZKSCAN1RF,
  title={Circ-ZKSCAN1 regulates FAM83A expression and inactivates MAPK signaling by targeting miR-330-5p to promote non-small cell lung cancer progression.},
  author={Yuanyong Wang and Rongjian Xu and D. Zhang and T. Lu and Wanpeng Yu and Y. Wo and Ao Liu and Tianyi Sui and J. Cui and Y. Qin and Y. Dong and X. Leng and Dezhi Kong and Wenxing Du and Z. Huang and Wenhao Su and Tianxiang Yuan and Xiao Sun and Jianxun Wang and W. Jiao},
  journal={Translational lung cancer research},
  year={2019},
  volume={8 6},
  pages={
          862-875
        }
}
  • Yuanyong Wang, Rongjian Xu, +17 authors W. Jiao
  • Published 2019
  • Medicine
  • Translational lung cancer research
Background Circular RNAs (circRNAs) belong to a new type of endogenous non-coding RNA and plays a key role in carcinogenesis. Circ-ZKSCAN1 (hsa_circ_0001727) has been proven to be a tumor-dependent circRNA. However, its role in non-small cell lung cancer (NSCLC) has been underreported. Methods The expression patterns of circ-ZKSCAN1 were determined using qRT-PCR in NSCLC samples and cell lines. Cell proliferation was examined utilizing the CCK-8 assay. Cell migration and invasion were… Expand
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