Circ-AASDH functions as the progression of early stage lung adenocarcinoma by targeting miR-140-3p to activate E2F7 expression.

@article{Wang2021CircAASDHFA,
  title={Circ-AASDH functions as the progression of early stage lung adenocarcinoma by targeting miR-140-3p to activate E2F7 expression.},
  author={Yuanyong Wang and Y. Wo and T. Lu and Xiao Sun and Ao Liu and Y. Dong and Wenxing Du and Wenhao Su and Z. Huang and W. Jiao},
  journal={Translational lung cancer research},
  year={2021},
  volume={10 1},
  pages={
          57-70
        }
}
  • Yuanyong Wang, Y. Wo, +7 authors W. Jiao
  • Published 2021
  • Medicine
  • Translational lung cancer research
Background Lung adenocarcinoma (LUAD), which is the most common subtype of non-small cell lung cancer, is a leading course of cancer-related mortality worldwide. Recently, circular RNA (CircRNAs) has become a hot spot in cancer research because of its important role in tumorigenesis and development and its superior stability. This study aims to clarify the role of circ-AASDH in LUAD and explore its competitive endogenous RNA mechanism. Methods The circ-AASDH, miR-140-3p and E2F transcription… Expand