Ciprofloxacin versus ceftriaxone in the treatment of multiresistant typhoid fever

  title={Ciprofloxacin versus ceftriaxone in the treatment of multiresistant typhoid fever},
  author={M. Wallace and A. A. Yousif and G. A. Mahroos and T. Mapes and E. J. Threlfall and B. Rowe and K. Hyams},
  journal={European Journal of Clinical Microbiology and Infectious Diseases},
  • M. Wallace, A. A. Yousif, +4 authors K. Hyams
  • Published 2005
  • Medicine
  • European Journal of Clinical Microbiology and Infectious Diseases
  • A randomized trial comparing ceftriaxone (3 g given parenterally per day for 7 days) to ciprofloxacin (500 mg given orally twice a day for 7 days) in the treatment of blood culture positive typhoid fever was conducted. Twenty patients were openly randomized to receive ciprofloxacin and 22 to receive ceftriaxone. The outcome was classified as clinical failure in 6 patients (27 %) in the ceftriaxone group, but in none in the ciprofloxacin group (p=0.01). The mean duration of fever was four days… CONTINUE READING
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