Ciprofloxacin pharmacokinetics in young cystic fibrosis patients after repeated oral doses.

@article{Odoul2001CiprofloxacinPI,
  title={Ciprofloxacin pharmacokinetics in young cystic fibrosis patients after repeated oral doses.},
  author={F. Odoul and Chantal Barin Le Guellec and C Giraut and Claire De Gialluly and Sophie Marchand and Gilles Paintaud and Marie Claude Saux and J. C. Rolland and Elisabeth Autret-Leca},
  journal={Therapie},
  year={2001},
  volume={56 5},
  pages={519-24}
}
Until recently, only compassionate use of ciprofloxacin in children with cystic fibrosis was possible despite limited pharmacokinetic data. We studied five subjects with cystic fibrosis and exacerbation of pulmonary infection. A 15 mg/kg b.i.d. regimen of oral ciprofloxacin was administered. On the 15th day, eight blood samples were collected and plasma… CONTINUE READING