Ciprofloxacin pharmacokinetic profiles in paediatric sepsis: how much ciprofloxacin is enough?

@article{Lipman2002CiprofloxacinPP,
  title={Ciprofloxacin pharmacokinetic profiles in paediatric sepsis: how much ciprofloxacin is enough?},
  author={Jeffrey Lipman and Andries Gs Gous and L Rudo Mathivha and Shephelia Tshukutsoane and Juan Scribante and Hubert Hon and Mary Pinder and Jacinto Riera-Fanego and Lia C. G. Verhoef and Heino Stass},
  journal={Intensive Care Medicine},
  year={2002},
  volume={28},
  pages={493-500}
}
Objective: To determine the pharmacokinetic profile of ciprofloxacin 20 mg/kg per day (10 mg/kg administered intravenously 12 hourly) in paediatric patients with severe sepsis. Design: Open and prospective. Setting: Tertiary referral multi-disciplinary ICU. Patients: Twenty patients (two groups – group A: 3 months–1 year; group B 1–5 years). Interventions… CONTINUE READING