Ciprofloxacin enhances T cell function by modulating interleukin activities.

  title={Ciprofloxacin enhances T cell function by modulating interleukin activities.},
  author={Karin St{\"u}nkel and Guy Hewlett and H J Zeiler},
  journal={Clinical and experimental immunology},
  volume={86 3},
Ciprofloxacin (CIP) is a quinolone carboxylic acid derivative with a broad spectrum of antibacterial activity. CIP (0.1-30 micrograms/ml) enhanced DNA synthesis of mouse spleen cells and human peripheral blood lymphocytes (PBL) that had been activated with T cell mitogens or with alloantigens. In addition, CIP increased the amount of IL-2 found in the supernatants of phytohaemagglutinin (PHA)-stimulated human PBL. The presence of CIP in the medium (0.3-10 micrograms/ml) increased the levels of… CONTINUE READING


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