• Corpus ID: 77910542

Cinanserin (SQ. 10,643): a preliminary evaluation in chronic schizophrenic patients.

@article{Dm1968Cinanserin1,
  title={Cinanserin (SQ. 10,643): a preliminary evaluation in chronic schizophrenic patients.},
  author={Gallant Dm and Bishop Mp},
  journal={Current Therapeutic Research-clinical and Experimental},
  year={1968},
  volume={10},
  pages={461}
}
  • Gallant Dm, Bishop Mp
  • Published 1 September 1968
  • Psychology
  • Current Therapeutic Research-clinical and Experimental
Schizophrenia: Nature of the Disease Process and its Biological Correlates
TLDR
The sections in this article are: Diagnosis, History, Nature of Psychological Deficit, Effectiveness of Drug Treatment, and Etiological Factors.
Identification and Evaluation of Coronavirus Replicase Inhibitors Using a Replicon Cell Line
TLDR
A non-cytopathic, selectable replicon RNA that can be stably maintained in eukaryotic cells is generated and could demonstrate a strong inhibitory activity of cinanserin and a strong inhibition of SARS-CoV and HCoV-229E replication in tissue culture is demonstrated.
Cinanserin Is an Inhibitor of the 3C-Like Proteinase of Severe Acute Respiratory Syndrome Coronavirus and Strongly Reduces Virus Replication In Vitro
TLDR
It is demonstrated that the old drug cinanserin is an inhibitor of SARS-CoV replication, acting most likely via inhibition of the 3CL proteinase.
Biochemistry of schizophrenia
TLDR
The theory that the primary disturbance in schizophrenia has a neurochemical basis is plausible because there has been a widely held view that there are no gross structural changes in the brains of schizophrenics.
Current Status and Perspectives of Pharmacotherapeutic Research Related to Schizophrenic Psychoses
Neuroleptics have now been available for antipsychotic treatment over more than 35 years. During this period valuable information has been obtained on the mechanism of action of neuroleptic drugs, on
Pharmakologie der Neuroleptika und relevante Mechanismen zur Behandlung von Minussymptomatik
TLDR
Neuere Untersuchungen haben bewiesen, das der Serotoninantagonismus die antipsychotische Wirkung der Dopaminantagonisten unterstutzt.
Serotonin Involvement in the Action of Antipsychotic Drugs
TLDR
The development of selective 5HT2 antagonists devoid of partial agonist activity revived the interest in the physiological and pathological role of serotonin.
[The neurochemistry of schizophrenia].
  • F. Owen, M. Simpson
  • Psychology, Medicine
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica
  • 1989
TLDR
The hypotheses of neurotransmitter dysfunction associated with schizophrenia that have generated significant research interest are listed in Table 6.1.
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