[Cimetidine inhibits the adhesion of cancer cells with sialyl Lewis epitope onto the vascular endothelium].

Abstract

The attachment of circulating cancer cells to vascular endothelium is considered an important initial step in hematogenous metastasis. We believe that hematogenous metastasis can be inhibited by blocking the adhesion of cancer cells to vascular endothelium. We demonstrated that cimetidine suppressed the expression of E-selectin on the surface of HUVECs… (More)

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@article{Hayashi2003CimetidineIT, title={[Cimetidine inhibits the adhesion of cancer cells with sialyl Lewis epitope onto the vascular endothelium].}, author={Atsuhiro Hayashi and Kenichi Kobayashi and Yoshihiro Imaeda and Sumio Matsumoto}, journal={Gan to kagaku ryoho. Cancer & chemotherapy}, year={2003}, volume={30 11}, pages={1788-90} }