Cimetidine induces coronary artery spasm in patients with vasospastic angina.

Abstract

We have previously reported that cimetidine, a histamine H2-receptor blocker, augments the histamine-induced coronary vasoconstriction at the site of spastic segments in the atherosclerotic coronary arteries of swine. To elucidate whether cimetidine has a coronary vasoconstrictive effect in humans, 14 patients with vasospastic angina (group 1) and 14… (More)

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Cite this paper

@article{Shimokawa1987CimetidineIC, title={Cimetidine induces coronary artery spasm in patients with vasospastic angina.}, author={Hiroaki Shimokawa and Shuichi Okamatsu and Yuji Taira and Masayuki Nakamura}, journal={The Canadian journal of cardiology}, year={1987}, volume={3 4}, pages={177-82} }