Cimetidine: A Review of its Pharmacological Properties and Therapeutic Efficacy in Peptic Ulcer Disease

@article{Brogden1978CimetidineAR,
  title={Cimetidine: A Review of its Pharmacological Properties and Therapeutic Efficacy in Peptic Ulcer Disease},
  author={Rex N. Brogden and Rennie C. Heel and Trevor M. Speight and Graeme S. Avery},
  journal={Drugs},
  year={1978},
  volume={15},
  pages={93-131}
}
  • Rex N. Brogden, Rennie C. Heel, +1 author Graeme S. Avery
  • Published 1978
  • Medicine
  • Drugs
  • SummarySynopsis: Cimetidine1 is a specific competitive histamine H2-receptor antagonist which effectively inhibits gastric acid secretion and is advocated for the treatment of chronic peptic ulceration, haemorrhage from erosive gastritis, and the control of gastric hypersecretion and peptic ulceration in the Zollinger-Ellison syndrome. Placebo-controlled trials in outpatients have demonstrated its efficacy in promoting the healing of endoscopically diagnosed duodenal ulceration, during a period… CONTINUE READING

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    • Medicine
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