Ciliary neurotrophic factor receptor alpha subunit-modulated multiple downstream signaling pathways in hepatic cancer cell lines and their biological implications.

@article{Hu2008CiliaryNF,
  title={Ciliary neurotrophic factor receptor alpha subunit-modulated multiple downstream signaling pathways in hepatic cancer cell lines and their biological implications.},
  author={Xin Hu and Yingjun Zhao and Xianghuo He and Jinjun Li and Tao Wang and Wei-ping Zhou and Dafang Wan and Hongyang Wang and Jianren Gu},
  journal={Hepatology},
  year={2008},
  volume={47 4},
  pages={1298-308}
}
UNLABELLED Ciliary neurotrophic factor (CNTF) plays important roles in a variety of tissues including neural and non-neural systems, but the function of CNTF and its receptor (CNTFR) in liver remains unclear. In this study, we demonstrate that CNTFRalpha is expressed heterogeneously in normal human liver and hepatocellular carcinoma (HCC) specimens but not… CONTINUE READING