Ciliary neurotrophic factor controls progenitor migration during remyelination in the adult rodent brain.

@article{Vernerey2013CiliaryNF,
  title={Ciliary neurotrophic factor controls progenitor migration during remyelination in the adult rodent brain.},
  author={Julien Vernerey and Magali Macchi and Karine Magalon and Myriam Cayre and Pascale Durbec},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2013},
  volume={33 7},
  pages={
          3240-50
        }
}
Ciliary neurotrophic factor (CNTF) has been shown to be expressed after brain lesions and in particular after demyelination. Here, we addressed the role of this cytokine in the regulation of neural progenitor migration in the adult rodent brain. Using an acute model of demyelination, we show that CNTF is strongly re-expressed after lesion and is involved in the postlesional mobilization of endogenous progenitors that participate in the myelin regenerative process. We show that CNTF controls the… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 55 REFERENCES

Ciliary neurotrophic factor mediates dopamine D2 receptor-induced CNS neurogenesis in adult mice.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2008
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Remyelination in the CNS: from biology to therapy

  • Nature Reviews Neuroscience
  • 2008
VIEW 1 EXCERPT
HIGHLY INFLUENTIAL