Cilia involvement in patterning and maintenance of the skeleton.

  title={Cilia involvement in patterning and maintenance of the skeleton.},
  author={Courtney J. Haycraft and Rosa A Serra},
  journal={Current topics in developmental biology},
Although the expression of cilia on chondrocytes was described over 40 years ago, the importance of this organelle in skeletal development and maintenance has only recently been recognized. Primary cilia are found on most mammalian cells and have been shown to play a role in chemosensation and mechanosensation. A growing number of human pleiotropic syndromes have been shown to be associated with ciliary or basal body dysfunction. Skeletal phenotypes, including alterations in limb patterning… CONTINUE READING

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