Cilia-based flow network in the brain ventricles

@article{Faubel2016CiliabasedFN,
  title={Cilia-based flow network in the brain ventricles},
  author={Regina Faubel and Christian Westendorf and Eberhard Bodenschatz and Gregor Eichele},
  journal={Science},
  year={2016},
  volume={353},
  pages={176-178}
}
Cerebrospinal fluid conveys many physiologically important signaling factors through the ventricular cavities of the brain. We investigated the transport of cerebrospinal fluid in the third ventricle of the mouse brain and discovered a highly organized pattern of cilia modules, which collectively give rise to a network of fluid flows that allows for precise transport within this ventricle. We also discovered a cilia-based switch that reliably and periodically alters the flow pattern so as to… CONTINUE READING

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