Cilazapril and captopril accelerate recovery from hypoxia in myocardial cell aggregates in culture.

@article{Rabkin1992CilazaprilAC,
  title={Cilazapril and captopril accelerate recovery from hypoxia in myocardial cell aggregates in culture.},
  author={Simon W. Rabkin},
  journal={Journal of cardiovascular pharmacology},
  year={1992},
  volume={19 3},
  pages={394-401}
}
We wished to determine whether angiotensin-converting enzyme (ACE) inhibition alters the effect of hypoxia and reoxygenation directly on the cardiac myocyte; to compare two different ACE inhibitors, one with and one without a sulfhydryl group (i.e., captopril and cilazapril), and to examine the potential interaction of these ACE inhibitors with agents that purportedly prevent the deleterious action of oxygen-derived free radicals. Ventricular myocytes were obtained from 7-day-old chick embryo… CONTINUE READING