Ciguatera and mannitol: experience with a new treatment regimen.

  title={Ciguatera and mannitol: experience with a new treatment regimen.},
  author={John H. Pearn and Richard J Lewis and Tibor Ruff and Mike Tait and Joseph Quinn and W Murtha and Greg King and Alexandra Mallett and Norman C Gillespie},
  journal={The Medical journal of Australia},
  volume={151 2},
Ciguatera is a distressing, hitherto-untreatable and not rare disease which results from the eating of ciguatoxin-contaminated fish from tropical and subtropical waters. We report here the results of a pilot study to assess the efficacy of mannitol therapy in ciguatera poisoning. Twelve adult patients (six men) have been treated, five of whom--who were ill acutely--experienced a significant benefit from this therapy, in three cases, with a hitherto-unexperienced dramatic reversal of symptoms… CONTINUE READING

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